Oral sildenafil therapy for the management of mild persistent pulmonary hypertension of the newborn in term neonates

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منابع مشابه

Prevalence of Persistent Pulmonary Hypertension of the Newborn and Associated Factors in Term Neonates Born in Southeast of Iran, 2020

 Background and purpose: Infants with persistent pulmonary hypertension (PPHN) are readmitted to hospital three times more than other infants or die after discharge. The disease imposes a high cost on families and health systems. In this study, for the first time, the prevalence of PPHN and associated factors were investigated in mature neonates born in southeast of Iran. Materials and methods...

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Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: a pilot randomized blinded study.

BACKGROUND Persistent pulmonary hypertension (PPHN) occurs in as many as 6.8 of 1000 live births. Mortality is approximately 10% to 20% with high-frequency ventilation, surfactant, inhaled nitric oxide, and extracorporeal membrane oxygenation but is much higher when these therapies are not available. Sildenafil is a phosphodiesterase inhibitor type 5 that selectively reduces pulmonary vascular ...

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ژورنال

عنوان ژورنال: Indian Journal of Child Health

سال: 2020

ISSN: 2349-6118,2349-6126

DOI: 10.32677/ijch.2020.v07.i10.005